Publications

Below is the current list of group publications (last updated September 19, 2018). Click the title for the weblink, please contact Prof. Nagl for info or full-text requests, see info at the footer.

Journal Articles
Book Chapters
Proceedings and other scientific manuscripts

A. Peer-reviewed Journal Articles

2018

(39) S. Nagl, Micro free-flow isoelectric focusing with integrated optical pH sensors, Eng. Life Sci., 2018, 18, 114-123
(38) S. A. Pfeiffer, B.M. Rudisch, P. Glaeser, M. Spanka, F. Nitschke, A.A. Robitzki, C. Schneider, S. Nagl, D. Belder, Continuous purification of reaction products by micro free-flow electrophoresis enabled by large area deep-UV fluorescence imaging, Anal. Bioanal. Chem., 2018, 410, 853-862

2017

(37) S.A. Pfeiffer, S. Nagl, On-chip photothermal analyte detection using integrated luminescent temperature sensors, Anal. Chem. 2017, 89, 9400-9406
(36) S.A. Pfeiffer, S.M. Borisov, S. Nagl, In-line monitoring of pH and oxygen during enzymatic reactions in off-the-shelf all-glass microreactors using integrated luminescent microsensors, Microchim. Acta 2017, 184, 621-626

2016

(35) C. Herzog, E. Poehler, A.J. Peretzki, S.M. Borisov, D. Aigner, T. Mayr, S. Nagl, Continuous on-chip fluorescence labelling, free-flow isoelectric focusing and marker-free isoelectric point determination of proteins and peptides, Lab Chip 2016, 16, 1565-1572
(34) E. Poehler, S.A. Pfeiffer, M. Herm, M. Gaebler, B. Busse, S. Nagl, Microchamber arrays with an integrated long luminescence lifetime pH sensor, Anal. Bioanal. Chem. 2016, 408, 2927-2935

2015

(33) E. Poehler, C. Herzog, C. Lotter, S.A. Pfeiffer, D. Aigner, T. Mayr, S. Nagl, Label-free microfluidic free-flow isoelectric focusing, pH gradient sensing and near real-time isoelectric point determination of biomolecules and blood plasma fractions, Analyst 2015, 140, 7496-7502
(32) S.A. Pfeiffer, S. Nagl, Microfluidic platforms employing integrated fluorescent or luminescent chemical sensors: A review of methods, scope and applications, Methods Appl. Fluoresc. 2015, 3, 034003
(31) C. Herzog, G.F.W. Jochem, P. Glaeser, S. Nagl, Gas removal in free-flow electrophoresis using an integrated nanoporous membrane, Microchim. Acta 2015, 182, 887-892
(30) E. Poehler, C. Herzog, M. Suendermann, S.A. Pfeiffer, S. Nagl, Development of microscopic time domain dual lifetime referencing luminescence detection for pH monitoring in microfluidic free-flow isoelectric focusing, Eng. Life Sci. 2015, 15, 276-285
(29) J. Cao, S. Nagl, E. Kothe, J.M. Köhler, Application of oxygen sensor microparticles for monitoring bacterial growth and characterization of dose/response functions in microfluidic screenings, Microchim. Acta 2015, 182, 385-394
(28) C. Hoera, S. Ohla, Z. Shu, E. Beckert, S. Nagl, D. Belder, An integrated microfluidic chip enabling control and spatially resolved monitoring of temperature in micro flow reactors, Anal. Bioanal. Chem. 2015, 407, 387-396

2014

(27) C. Herzog, E. Beckert, S. Nagl, Rapid isoelectric point determination in a miniaturized preparative separation using jet-dispensed optical pH sensors and micro free-flow electrophoresis, Anal. Chem. 2014, 86, 9533–9539

2013

(26) S. Jezierski, V. Tehsmer, S. Nagl, D. Belder, Integrating microflow reactions with subsequent continuous product separation in a single microfluidic chip, Chem. Commun. 2013, 49, 11644-11646
(25) R. Beyreiss, D. Geißler, S. Ohla, S. Nagl, T.N. Posch, D. Belder, Label-free fluorescence detection of aromatic compounds in chip electrophoresis applying two photon excitation and time-correlated single photon counting, Anal. Chem. 2013, 85, 8150–8157
(24) C. Benz, H. Retzbach, S. Nagl, D. Belder, Protein-protein interaction analysis in single microfluidic droplets using FRET and fluorescence lifetime detection, Lab Chip 2013, 13, 2808-2814
(23) S. Jezierski, A.S. Klein, C. Benz, M. Schaefer, S. Nagl, D. Belder, Towards an integrated device that utilizes adherent cells in a micro-free-flow electrophoresis chip to achieve separation and biosensing, Anal. Bioanal. Chem. 2013, 405, 5381-5386
(22) S. Jezierski, D. Belder, S. Nagl, Microfluidic free-flow electrophoresis chips with an integrated fluorescent sensor layer for real time pH imaging in isoelectric focusing, Chem. Commun. 2013, 49, 904-906
(21) N. Rudolph, A.B. Moradi, S. Nagl, S.E. Oswald, Spatiotemporal mapping of local soil pH changes induced by roots of lupin and soft-rush, Plant Soil 2013, 369, 669–680
(20) L. Gitlin, C. Höra, R.J. Meier, S. Nagl, D. Belder, Micro flow reactor chips with integrated luminescent chemosensors for spatially resolved on-line chemical reaction monitoring, Lab Chip 2013, 13, 4134-4141

2012

(19) S. Köhler, S. Nagl, S. Fritzsche, D. Belder, Label-free Detection in Microchip Free-Flow Electrophoresis using Deep UV Laser Scanning Fluorescence Detection, Lab Chip 2012, 12, 458-463
(18) N. Rudolph, H.G. Esser, A. Carminati, A.B. Moradi, N. Kardjilov, S. Nagl, S.E. Oswald, Dynamic oxygen mapping in the root zone by fluorescence dye imaging combined with neutron radiography, J. Soils Sediments 2012, 12, 63-74
(17) S. Ohla, R. Beyreiss, S. Fritzsche, P. Gläser, S. Nagl, K. Stockhausen, C. Schneider, D. Belder, Monitoring on-Chip Pictet-Spengler Reactions by Integrated Analytical Separation and Label-Free Time-Resolved Fluorescence, Chem. Eur. J. 2012, 18, 1240-1246

2011

(16) S. Jezierski, L. Gitlin, S. Nagl, D. Belder, Multistep Liquid Phase Lithography for Fast Prototyping of Microfluidic Free-Flow-Electrophoresis Chips, Anal. Bioanal. Chem. 2011, 401, 2651-2656
(15) R. Beyreiss, S. Ohla, S. Nagl, D. Belder, Label-Free Analysis in Chip Electrophoresis Applying Deep UV Fluorescence Lifetime Detection, Electrophoresis 2011, 32, 3108-3114
(14) S. Nagl, P. Schulze, S. Ohla, R. Beyreiss, L. Gitlin, D. Belder, Microfluidic chips for chirality exploration, Anal. Chem. 2011, 83, 3232–3238
(13) D. Posavec, A. Dorsch, U. Bogner, G. Bernhardt, S. Nagl, Polyvinyl butyral nanobeads: Preparation, characterization, biocompatibility and cancer cell uptake, Microchim. Acta 2011, 173, 391-399
(12) D. Belder, K. Tolba, S. Nagl, Rapid quantitative determination of ephedra alkaloids in tablet formulations and human urine by microchip electrophoresis, Electrophoresis 2011, 32, 440–447

2009

(11) S. Nagl, P. Schulze, M. Ludwig, D. Belder, Progress in microchip enantioseparations, Electrophoresis 2009, 30, 2765-2772
(10) S. Nagl, M.I.J. Stich, M. Schaeferling, O.S. Wolfbeis, A method for simultaneous luminescence sensing and imaging of two species using optical probes of different decay time, Anal. Bioanal. Chem. 2009, 393, 1199-1207

2008

(9) C. Baleizão, S. Nagl, M. Schäferling, M.N. Berberan-Santos, O.S. Wolfbeis, Dual Fluorescence Sensor for Temperature and Trace Oxygen, Anal. Chem. 2008, 80, 6449-6457
(8) S. Nagl, R. Bauer, U. Sauer, C. Preininger, U. Bogner, M. Schaeferling, Microarray Analysis of Protein-Protein Interactions Based on FRET Using Subnanosecond-resolved Fluorescence Lifetime Imaging, Biosens. Bioelectron. 2008, 24, 397-402
(7) A.S. Kocincová, S. Nagl, S. Arain, C. Krause, S.M. Borisov, M. Arnold, O.S. Wolfbeis, Multiplex bacterial growth monitoring in 24-well microplates using a dual optical sensor for dissolved oxygen and pH, Biotechnol. Bioeng. 2008, 100, 430-438
(6) M.I.J. Stich, S. Nagl, O.S. Wolfbeis, U. Henne, M. Schäferling, Dual Fluorescent Sensor Material for Simultaneous Imaging of Pressure and Temperature on Surfaces, Adv. Funct. Mater. 2008, 18, 1399-1406

2007

(5) S. Nagl, O.S. Wolfbeis, Optical Multiple Chemical Sensing - Status and Current Challenges, Analyst 2007, 132, 507-511
(4) S. Nagl, C. Baleizão, S.M. Borisov, M. Schaeferling, M.N. Berberan-Santos, O.S. Wolfbeis, Optical Sensing and Imaging of Trace Oxygen with Record Response, Angew. Chem. Int. Ed. 2007, 46, 2317-2319
(3) C. Baleizão, S. Nagl, S.M. Borisov, M. Schäferling, O.S. Wolfbeis, M.N. Berberan-Santos, An Optical Thermometer Based on the Delayed Fluorescence of C70, Chem. Eur. J. 2007, 13, 3643-3651

2006

(2) M. Schäferling, S. Nagl, Optical Technologies for the Read Out and Quality Control of DNA and Protein Microarrays, Anal. Bioanal. Chem. 2006, 385, 500-517.

2005

(1) S. Nagl, M. Schäferling, O.S. Wolfbeis, Fluorescence Analysis in Microarray Technology, Microchim. Acta 2005, 151, 1-21

B. Peer-reviewed book chapters


(4) S. Nagl, Microfluidic free-flow isoelectric focusing with real-time pI determination in Microfluidic Electrophoresis: Methods in Molecular Biology vol. tbd, D. Dutta (ed.) Springer/Humana Press, Ottawa, in press
(3) M. Schäferling, S. Nagl, Förster Resonance Energy Transfer Methods for Quantification of Protein-Protein Interactions on Microarrays, pp. 303-320 in Protein Microarray for Disease Analysis: Methods and Protocols, Methods in Molecular Biology vol. 723, Catherine J. Wu (ed.) Springer/Humana Press, Ottawa, 2011
(2) S. Nagl, O.S. Wolfbeis, Classification of Chemical Sensors and Biosensors Based on Fluorescence and Phosphorescence , Springer Series on Fluorescence 5 - Standardization and Quality Assurance in Fluorescence Measurements 1: Techniques, U. Resch-Genger (ed.) Springer, Berlin, 2008
(1) S.M. Borisov, T. Mayr, A. Karasyov, I. Klimant, P. Chojnacki, C. Moser, S. Nagl, M. Schäferling, M.I.J. Stich, G.S. Vasilevskaya, O.S. Wolfbeis, New Plastic Microparticles and Nanoparticles for Fluorescent Sensing and Encoding, Springer Series on Fluorescence 4 - Fluorescence of Supermolecules, Polymers and Nanosystems, Mário N. Berberan-Santos (ed.) Springer, Berlin, 2008

C. Conference Proceedings and other scientific manuscripts


(10) E. Poehler, C. Herzog, S.A. Pfeiffer, C. Lotter, A.J. Peretzki, D. Aigner, T. Mayr, E. Beckert, S. Nagl, Application of Optical pH Sensors in the Microfluidic Free-flow Isoelectric Focusing of Biomolecules, Procedia Engineering 2015, 120, 175-179
(9) C. Herzog, A. Peretzki, D. Aigner, T. Mayr, S. Nagl, Microchip free-flow isoelectric focusing using a photolithographically integrated NIR fluorescent pH sensor layer, Proc. MicroTAS 2014, 2155-2157
(8) E. Poehler, S. Nagl, Fluoreszente Biosensorik in Mikrofluidikchips mit integrierten nanoporösen Glasmembranen, 11. Dresdner Sensor-Symposium Tagungsband 2013, 304-307
(7) C. Höra, Z. Shu, E. Beckert, S. Nagl, D. Belder, Integration fluoreszenter Temperatursensoren und resistiver Mikroheizer in mikrofluidische Durchflussreaktoren, 11. Dresdner Sensor-Symposium Tagungsband 2013, 289-293
(6) C. Herzog, E. Beckert, S. Nagl, Integration fluoreszenter Mikrosensoren in mikrofluidische Elektrophoreseplattformen mittels Tintenstrahldruck und Photopolymerisation, 11. Dresdner Sensor-Symposium Tagungsband 2013, 269-272
(5) S. Nagl, L. Gitlin, C. Herzog, C. Hoera, S. Jezierski, Z. Shu, E. Beckert, D. Belder, Fluoreszente chemischen Sensoren und Biosensoren in Mikrodurchflussreaktoren und miniaturisierten Elektrophoreseplattformen, 11. Dresdner Sensor-Symposium Tagungsband 2013, 97 - 101
(4) C. Höra, Z. Shu, E. Beckert, S. Nagl, D. Belder, Microfluidic flow reactors with integrated micro-heaters and fluorescent temperature sensors for reaction monitoring, Proc. MicroTAS 2013, 784-786
(3) C. Herzog, E. Beckert, S. Nagl, Integration of fluorescent pH sensors in microfluidic free-flow isoelectric focusing platforms using automated inkjet printing, Proc. MicroTAS 2013, 1209-1211
(2) S. Orthaus, M. König, S. Tannert, T. Schönau, K. Lauritsen, F. Koberling, R. Erdmann, R. Beyreiss, S. Nagl, D. Belder, Crossing the border towards deep UV time-resolved microscopy of native fluorophores, Eur. Biophys. J. 2013, 42, S104
(1) S. Nagl, Fluorescent Multiple Chemical Sensing using Time-Domain Fluorescence Lifetime Imaging, Doctoral Thesis, Universität Regensburg 2008